Misono Yakuhin

Misono Yakuhin is a historic pharmacy and cosmetic boutique in Nantan, Kyoto, established in 1913. It is the birthplace and exclusive retailer of "Misono Tsuru Tsuru Cream," a cult-favorite skincare product originally formulated for geishas and actors to heal skin damaged by heavy stage makeup. The business operates as the storefront for Misono Cosme, specializing in traditional, high-quality moisturizing solutions that have garnered a loyal following across Japan.